Bioactivity | [Nle8,18,Tyr34]-pTH (3-34) amide (bovine) ([Nle8'18,Tyr34]bPTH (3-34) amide) is an analogue of parathyroid hormone (PTH), and is a competitive inhibitor of PTH-stimulated biological responses in vitro[1]. |
CAS | 64297-16-1 |
Sequence | Ser-Glu-Ile-Gln-Phe-{Nle}-His-Asn-Leu-Gly-Lys-His-Leu-Ser-Ser-{Nle}-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Tyr-NH2 |
Shortening | SEIQF-{Nle}-HNLGKHLSS-{Nle}-ERVEWLRKKLQDVHNY-NH2 |
Formula | C177H279N53O48 |
Molar Mass | 3917.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Gray DA, et al. In vitro studies on an antagonist of parathyroid hormone [Nle-8, Nle-18, Tyr-34]bPTH-(3-34)amide. Br J Pharmacol. 1982 Jun;76(2):259-63. [2]. Segre GV, et al. Evaluation of an in vitro parathyroid hormone antagonist in vivo in dogs. Endocrinology. 1985 Mar;116(3):1024-9. |